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Statistical inference for time course RNA-Seq data using a negative binomial mixed-effect model
BACKGROUND: Accurate identification of differentially expressed (DE) genes in time course RNA-Seq data is crucial for understanding the dynamics of transcriptional regulatory network. However, most of the available methods treat gene expressions at different time points as replicates and test the si...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5002174/ https://www.ncbi.nlm.nih.gov/pubmed/27565575 http://dx.doi.org/10.1186/s12859-016-1180-9 |