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Dysregulation of the (immuno)proteasome pathway in malformations of cortical development

BACKGROUND: The proteasome is a multisubunit enzyme complex involved in protein degradation, which is essential for many cellular processes. During inflammation, the constitutive subunits are replaced by their inducible counterparts, resulting in the formation of the immunoproteasome. METHODS: We in...

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Detalles Bibliográficos
Autores principales: van Scheppingen, J., Broekaart, D. W. M., Scholl, T., Zuidberg, M. R. J., Anink, J. J., Spliet, W. G., van Rijen, P. C., Czech, T., Hainfellner, J. A., Feucht, M., Mühlebner, A., van Vliet, E. A., Aronica, E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5002182/
https://www.ncbi.nlm.nih.gov/pubmed/27566410
http://dx.doi.org/10.1186/s12974-016-0662-z