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Molecular and structural considerations of TF-DNA binding for the generation of biologically meaningful and accurate phylogenetic footprinting analysis: the LysR-type transcriptional regulator family as a study model

BACKGROUND: The goal of most programs developed to find transcription factor binding sites (TFBSs) is the identification of discrete sequence motifs that are significantly over-represented in a given set of sequences where a transcription factor (TF) is expected to bind. These programs assume that t...

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Detalles Bibliográficos
Autores principales: Oliver, Patricia, Peralta-Gil, Martín, Tabche, María-Luisa, Merino, Enrique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5002191/
https://www.ncbi.nlm.nih.gov/pubmed/27567672
http://dx.doi.org/10.1186/s12864-016-3025-3