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Synergism and the mechanism of action of the combination of α-mangostin isolated from Garcinia mangostana L. and oxacillin against an oxacillin-resistant Staphylococcus saprophyticus

BACKGROUND: Globally, staphylococci have developed resistance to many antibiotics. New approaches to chemotherapy are needed and one such approach could be to use plant derived actives with conventional antibiotics in a synergestic way. The purpose of this study was to isolate α-mangostin from the m...

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Detalles Bibliográficos
Autores principales: Phitaktim, Sineewan, Chomnawang, Mullika, Sirichaiwetchakoon, Kittipot, Dunkhunthod, Benjawan, Hobbs, Glyn, Eumkeb, Griangsak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5002192/
https://www.ncbi.nlm.nih.gov/pubmed/27566110
http://dx.doi.org/10.1186/s12866-016-0814-4