Development of a protein–ligand-binding site prediction method based on interaction energy and sequence conservation

We present a new method for predicting protein–ligand-binding sites based on protein three-dimensional structure and amino acid conservation. This method involves calculation of the van der Waals interaction energy between a protein and many probes placed on the protein surface and subsequent cluste...

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Detalles Bibliográficos
Autores principales: Tsujikawa, Hiroto, Sato, Kenta, Wei, Cao, Saad, Gul, Sumikoshi, Kazuya, Nakamura, Shugo, Terada, Tohru, Shimizu, Kentaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5002282/
https://www.ncbi.nlm.nih.gov/pubmed/27400687
http://dx.doi.org/10.1007/s10969-016-9204-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5002282/
https://www.ncbi.nlm.nih.gov/pubmed/27400687
http://dx.doi.org/10.1007/s10969-016-9204-2

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