Cargando…

Interaction between synaptic inhibition and glial-potassium dynamics leads to diverse seizure transition modes in biophysical models of human focal seizures

How focal seizures initiate and evolve in human neocortex remains a fundamental problem in neuroscience. Here, we use biophysical neuronal network models of neocortical patches to study how the interaction between inhibition and extracellular potassium ([K (+)](o)) dynamics may contribute to differe...

Descripción completa

Detalles Bibliográficos
Autores principales: Y. Ho, E. C., Truccolo, Wilson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5002283/
https://www.ncbi.nlm.nih.gov/pubmed/27488433
http://dx.doi.org/10.1007/s10827-016-0615-7