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Micro-RNA-21 (biomarker) and global longitudinal strain (functional marker) in detection of myocardial fibrotic burden in severe aortic valve stenosis: a pilot study

AIMS: Myocardial fibrosis (MF) is a deleterious consequence of aortic valve stenosis (AVS). Global longitudinal strain (GLS) is a novel left ventricular (LV) functional parameter potentially useful to non-invasively estimate MF. MicroRNAs (miRNAs) are non-coding small ribonucleic acids (RNA) modulat...

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Detalles Bibliográficos
Autores principales: Fabiani, Iacopo, Scatena, Cristian, Mazzanti, Chiara Maria, Conte, Lorenzo, Pugliese, Nicola Riccardo, Franceschi, Sara, Lessi, Francesca, Menicagli, Michele, De Martino, Andrea, Pratali, Stefano, Bortolotti, Uberto, Naccarato, Antonio Giuseppe, La Carrubba, Salvatore, Di Bello, Vitantonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5002330/
https://www.ncbi.nlm.nih.gov/pubmed/27567668
http://dx.doi.org/10.1186/s12967-016-1011-9