Cargando…

Dependence of RIG-I Nucleic Acid-Binding and ATP Hydrolysis on Activation of Type I Interferon Response

Exogenous nucleic acids induce an innate immune response in mammalian host cells through activation of the retinoic acid-inducible gene I (RIG-I). We evaluated RIG-I protein for RNA binding and ATPase stimulation with RNA ligands to investigate the correlation with the extent of immune response thro...

Descripción completa

Detalles Bibliográficos
Autores principales: Baek, Yu Mi, Yoon, Soojin, Hwang, Yeo Eun, Kim, Dong-Eun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Immunologists 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5002451/
https://www.ncbi.nlm.nih.gov/pubmed/27574504
http://dx.doi.org/10.4110/in.2016.16.4.249