Astrocyte‐mediated regulation of multidrug resistance p‐glycoprotein in fetal and neonatal brain endothelial cells: age‐dependent effects

Brain endothelial cells (BECs) form a major component of the blood–brain barrier (BBB). In late gestation, these cells express high levels of the multidrug transporter p‐glycoprotein (P‐gp; encoded by Abcb1), which prevents the passage of an array of endogenous factors and xenobiotics into the fetal...

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Detalles Bibliográficos
Autores principales: Baello, Stephanie, Iqbal, Majid, Gibb, William, Matthews, Stephen G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5002904/
https://www.ncbi.nlm.nih.gov/pubmed/27796269
http://dx.doi.org/10.14814/phy2.12853

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5002904/
https://www.ncbi.nlm.nih.gov/pubmed/27796269
http://dx.doi.org/10.14814/phy2.12853

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