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Astrocyte‐mediated regulation of multidrug resistance p‐glycoprotein in fetal and neonatal brain endothelial cells: age‐dependent effects
Brain endothelial cells (BECs) form a major component of the blood–brain barrier (BBB). In late gestation, these cells express high levels of the multidrug transporter p‐glycoprotein (P‐gp; encoded by Abcb1), which prevents the passage of an array of endogenous factors and xenobiotics into the fetal...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5002904/ https://www.ncbi.nlm.nih.gov/pubmed/27796269 http://dx.doi.org/10.14814/phy2.12853 |