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ADAM17 and EGFR regulate IL‐6 receptor and amphiregulin mRNA expression and release in cigarette smoke‐exposed primary bronchial epithelial cells from patients with chronic obstructive pulmonary disease (COPD)

Aberrant activity of a disintegrin and metalloprotease 17 (ADAM17), also known as TACE, and epidermal growth factor receptor (EGFR) has been suggested to contribute to chronic obstructive pulmonary disease (COPD) development and progression. The aim of this study was to investigate the role of these...

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Detalles Bibliográficos
Autores principales: Stolarczyk, Marta, Amatngalim, Gimano D., Yu, Xiao, Veltman, Mieke, Hiemstra, Pieter S., Scholte, Bob J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5002905/
https://www.ncbi.nlm.nih.gov/pubmed/27561911
http://dx.doi.org/10.14814/phy2.12878