Cargando…
ADAM17 and EGFR regulate IL‐6 receptor and amphiregulin mRNA expression and release in cigarette smoke‐exposed primary bronchial epithelial cells from patients with chronic obstructive pulmonary disease (COPD)
Aberrant activity of a disintegrin and metalloprotease 17 (ADAM17), also known as TACE, and epidermal growth factor receptor (EGFR) has been suggested to contribute to chronic obstructive pulmonary disease (COPD) development and progression. The aim of this study was to investigate the role of these...
Autores principales: | Stolarczyk, Marta, Amatngalim, Gimano D., Yu, Xiao, Veltman, Mieke, Hiemstra, Pieter S., Scholte, Bob J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5002905/ https://www.ncbi.nlm.nih.gov/pubmed/27561911 http://dx.doi.org/10.14814/phy2.12878 |
Ejemplares similares
-
The EGFR-ADAM17 Axis in Chronic Obstructive Pulmonary Disease and Cystic Fibrosis Lung Pathology
por: Stolarczyk, Marta, et al.
Publicado: (2018) -
Airway Epithelial Cell Function and Respiratory Host Defense in Chronic Obstructive Pulmonary Disease
por: Amatngalim, Gimano D., et al.
Publicado: (2018) -
Cigarette Smoke Modulates Repair and Innate Immunity following Injury to Airway Epithelial Cells
por: Amatngalim, Gimano D., et al.
Publicado: (2016) -
ADAM17 is essential for ectodomain shedding of the EGF‐receptor ligand amphiregulin
por: Hosur, Vishnu, et al.
Publicado: (2018) -
Contribution of Host Defence Proteins and Peptides to Host-Microbiota Interactions in Chronic Inflammatory Lung Diseases
por: van der Does, Anne M., et al.
Publicado: (2018)