BMI1 is downregulated by the natural compound curcumin, but not by bisdemethoxycurcumin and dimethoxycurcumin

The B‐cell‐specific Moloney murine leukemia virus integration site 1 (BMI1) locus encodes a 37‐kD protein that is a key regulatory component of the polycomb regulatory complex 1 (PRC1). When overexpressed in various cancer types, the BMI1 protein induces cell growth and promotes tumor growth in vitr...

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Detalles Bibliográficos
Autores principales: Adeyeni, Temitope A., Khatwani, Natasha, San, KayKay, Ezekiel, Uthayashanker R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5002914/
https://www.ncbi.nlm.nih.gov/pubmed/27550987
http://dx.doi.org/10.14814/phy2.12906

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5002914/
https://www.ncbi.nlm.nih.gov/pubmed/27550987
http://dx.doi.org/10.14814/phy2.12906

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