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BMI1 is downregulated by the natural compound curcumin, but not by bisdemethoxycurcumin and dimethoxycurcumin

The B‐cell‐specific Moloney murine leukemia virus integration site 1 (BMI1) locus encodes a 37‐kD protein that is a key regulatory component of the polycomb regulatory complex 1 (PRC1). When overexpressed in various cancer types, the BMI1 protein induces cell growth and promotes tumor growth in vitr...

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Detalles Bibliográficos
Autores principales:	Adeyeni, Temitope A., Khatwani, Natasha, San, KayKay, Ezekiel, Uthayashanker R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5002914/ https://www.ncbi.nlm.nih.gov/pubmed/27550987 http://dx.doi.org/10.14814/phy2.12906

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