Female mice lacking Xist RNA show partial dosage compensation and survive to term

X-chromosome inactivation (XCI) compensates for differences in X-chromosome number between male and female mammals. XCI is orchestrated by Xist RNA, whose expression in early development leads to transcriptional silencing of one X chromosome in the female. Knockout studies have established a require...

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Detalles Bibliográficos
Autores principales: Yang, Lin, Kirby, James E., Sunwoo, Hongjae, Lee, Jeannie T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5002979/
https://www.ncbi.nlm.nih.gov/pubmed/27542829
http://dx.doi.org/10.1101/gad.281162.116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5002979/
https://www.ncbi.nlm.nih.gov/pubmed/27542829
http://dx.doi.org/10.1101/gad.281162.116

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