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Codon usage affects the structure and function of the Drosophila circadian clock protein PERIOD

Codon usage bias is a universal feature of all genomes, but its in vivo biological functions in animal systems are not clear. To investigate the in vivo role of codon usage in animals, we took advantage of the sensitivity and robustness of the Drosophila circadian system. By codon-optimizing parts o...

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Detalles Bibliográficos
Autores principales: Fu, Jingjing, Murphy, Katherine A., Zhou, Mian, Li, Ying H., Lam, Vu H., Tabuloc, Christine A., Chiu, Joanna C., Liu, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5002980/
https://www.ncbi.nlm.nih.gov/pubmed/27542830
http://dx.doi.org/10.1101/gad.281030.116