Phenotypic Characterization of Toxic Compound Effects on Liver Spheroids Derived from iPSC Using Confocal Imaging and Three-Dimensional Image Analysis

Cell models are becoming more complex to better mimic the in vivo environment and provide greater predictivity for compound efficacy and toxicity. There is an increasing interest in exploring the use of three-dimensional (3D) spheroids for modeling developmental and tissue biology with the goal of a...

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Detalles Bibliográficos
Autores principales: Sirenko, Oksana, Hancock, Michael K., Hesley, Jayne, Hong, Dihui, Cohen, Avrum, Gentry, Jason, Carlson, Coby B., Mann, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003004/
https://www.ncbi.nlm.nih.gov/pubmed/27494736
http://dx.doi.org/10.1089/adt.2016.729

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003004/
https://www.ncbi.nlm.nih.gov/pubmed/27494736
http://dx.doi.org/10.1089/adt.2016.729

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