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Structure and function of the bacterial decapping enzyme NudC

RNA capping and decapping are thought to be distinctive features of eukaryotes. Recently, the redox cofactor NAD was discovered to be attached to small regulatory RNAs in bacteria in a cap-like manner, and Nudix hydrolase NudC was found to act as a NAD decapping enzyme in vitro and in vivo. Here, cr...

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Detalles Bibliográficos
Autores principales: Höfer, Katharina, Li, Sisi, Abele, Florian, Frindert, Jens, Schlotthauer, Jasmin, Grawenhoff, Julia, Du, Jiamu, Patel, Dinshaw J., Jäschke, Andres
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003112/
https://www.ncbi.nlm.nih.gov/pubmed/27428510
http://dx.doi.org/10.1038/nchembio.2132