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Coupling Protein Dynamics with Proton Transport in Human Carbonic Anhydrase II

[Image: see text] The role of protein dynamics in enzyme catalysis is one of the most highly debated topics in enzymology. The main controversy centers around what may be defined as functionally significant conformational fluctuations and how, if at all, these fluctuations couple to enzyme catalyzed...

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Detalles Bibliográficos
Autores principales: Taraphder, Srabani, Maupin, C. Mark, Swanson, Jessica M. J., Voth, Gregory A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003118/
https://www.ncbi.nlm.nih.gov/pubmed/27063577
http://dx.doi.org/10.1021/acs.jpcb.6b02166