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eIF3d is an mRNA cap-binding protein required for specialized translation initiation

Eukaryotic mRNAs contain a 5' cap structure critical for recruitment of the translation machinery and initiation of protein synthesis. mRNA recognition is thought to require direct interactions between eukaryotic initiation factor 4E (eIF4E) and the mRNA cap. However, translation of numerous ca...

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Detalles Bibliográficos
Autores principales: Lee, Amy S.Y., Kranzusch, Philip J., Doudna, Jennifer A., Cate, Jamie H.D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003174/
https://www.ncbi.nlm.nih.gov/pubmed/27462815
http://dx.doi.org/10.1038/nature18954