Cargando…
eIF3d is an mRNA cap-binding protein required for specialized translation initiation
Eukaryotic mRNAs contain a 5' cap structure critical for recruitment of the translation machinery and initiation of protein synthesis. mRNA recognition is thought to require direct interactions between eukaryotic initiation factor 4E (eIF4E) and the mRNA cap. However, translation of numerous ca...
Autores principales: | Lee, Amy S.Y., Kranzusch, Philip J., Doudna, Jennifer A., Cate, Jamie H.D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003174/ https://www.ncbi.nlm.nih.gov/pubmed/27462815 http://dx.doi.org/10.1038/nature18954 |
Ejemplares similares
-
eIF3 targets cell proliferation mRNAs for translational activation or repression
por: Lee, Amy S.Y., et al.
Publicado: (2015) -
Two RNA-binding motifs in eIF3 direct HCV IRES-dependent translation
por: Sun, Chaomin, et al.
Publicado: (2013) -
Sapovirus Translation Requires an Interaction between VPg and the Cap Binding Protein eIF4E
por: Hosmillo, Myra, et al.
Publicado: (2014) -
Robust T cell activation requires an eIF3-driven burst in T cell receptor translation
por: De Silva, Dasmanthie, et al.
Publicado: (2021) -
Cellular mRNA recruits the ribosome via eIF3-PABP bridge to initiate internal translation
por: Thakor, Nehal, et al.
Publicado: (2016)