Sensitization to and Challenge with Gliadin Induce Pancreatitis and Extrapancreatic Inflammation in HLA-DQ8 Mice: An Animal Model of Type 1 Autoimmune Pancreatitis

BACKGROUND/AIMS: The aim of this study was to establish a pathogenetic mechanism of pancreatitis in celiac disease and IgG4-related disease using gluten-sensitive human leukocyte antigen (HLA)-DQ8 transgenic mice. METHODS: Transgenic mice expressing HLA-DQ8 genes were utilized. Control mice were not...

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Detalles Bibliográficos
Autores principales: Moon, Sung-Hoon, Kim, Jihun, Kim, Mi-Young, Park, Do Hyun, Song, Tae Jun, Kim, Sun A, Lee, Sang Soo, Seo, Dong Wan, Lee, Sung Koo, Kim, Myung-Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial Office of Gut and Liver 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003210/
https://www.ncbi.nlm.nih.gov/pubmed/27114422
http://dx.doi.org/10.5009/gnl15484

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003210/
https://www.ncbi.nlm.nih.gov/pubmed/27114422
http://dx.doi.org/10.5009/gnl15484

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