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Sensitization to and Challenge with Gliadin Induce Pancreatitis and Extrapancreatic Inflammation in HLA-DQ8 Mice: An Animal Model of Type 1 Autoimmune Pancreatitis
BACKGROUND/AIMS: The aim of this study was to establish a pathogenetic mechanism of pancreatitis in celiac disease and IgG4-related disease using gluten-sensitive human leukocyte antigen (HLA)-DQ8 transgenic mice. METHODS: Transgenic mice expressing HLA-DQ8 genes were utilized. Control mice were not...
Autores principales: | Moon, Sung-Hoon, Kim, Jihun, Kim, Mi-Young, Park, Do Hyun, Song, Tae Jun, Kim, Sun A, Lee, Sang Soo, Seo, Dong Wan, Lee, Sung Koo, Kim, Myung-Hwan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Editorial Office of Gut and Liver
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003210/ https://www.ncbi.nlm.nih.gov/pubmed/27114422 http://dx.doi.org/10.5009/gnl15484 |
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