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Structures of Ebola Virus GP and sGP in Complex with Therapeutic Antibodies

The Ebola virus (EBOV) GP gene encodes two glycoproteins. The major product is a soluble, dimeric glycoprotein termed sGP that is secreted abundantly. Despite the abundance of sGP during infection, little is known regarding its structure or functional role. A minor product, resulting from transcript...

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Detalles Bibliográficos
Autores principales: Pallesen, Jesper, Murin, Charles D., de Val, Natalia, Cottrell, Christopher A., Hastie, Kathryn M., Turner, Hannah L., Fusco, Marnie L., Flyak, Andrew I., Zeitlin, Larry, Crowe, James E., Andersen, Kristian G., Saphire, Erica Ollmann, Ward, Andrew B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003320/
https://www.ncbi.nlm.nih.gov/pubmed/27562261
http://dx.doi.org/10.1038/nmicrobiol.2016.128