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Development of 2, 7-Diamino-1, 8-Naphthyridine (DANP) Anchored Hairpin Primers for RT-PCR Detection of Chikungunya Virus Infection

A molecular diagnostic platform with DANP-anchored hairpin primer was developed and evaluated for the rapid and cost-effective detection of Chikungunya virus (CHIKV) with high sensitivity and specificity. The molecule 2, 7-diamino-1, 8-naphthyridine (DANP) binds to a cytosine-bulge and emits fluores...

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Detalles Bibliográficos
Autores principales: Chen, Huixin, Parimelalagan, Mariya, Takei, Fumie, Hapuarachchi, Hapuarachchige Chanditha, Koay, Evelyn Siew-Chuan, Ng, Lee Ching, Ho, Phui San, Nakatani, Kazuhiko, Chu, Justin Jang Hann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003370/
https://www.ncbi.nlm.nih.gov/pubmed/27571201
http://dx.doi.org/10.1371/journal.pntd.0004887