A Model to Explain How the Bacille Calmette Guérin (BCG) Vaccine Drives Interleukin-12 Production in Neonates

The Bacille Calmette Guérin (BCG) vaccine is the only routine vaccination at birth that effectively induces neonatal T-helper 1 (Th1)-polarized immune responses. The primary cytokine that drives CD4+ T-cell Th1 differentiation is interleukin (IL)-12 p70, a heterodimeric cytokine composed of the IL-1...

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Detalles Bibliográficos
Autores principales: Kativhu, Chido Loveness, Libraty, Daniel H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003384/
https://www.ncbi.nlm.nih.gov/pubmed/27571272
http://dx.doi.org/10.1371/journal.pone.0162148

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003384/
https://www.ncbi.nlm.nih.gov/pubmed/27571272
http://dx.doi.org/10.1371/journal.pone.0162148

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