Development and Optimization of a Thrombin Sandwich Aptamer Microarray

A sandwich microarray employing two distinct aptamers for human thrombin has been optimized for the detection of subnanomolar concentrations of the protein. The aptamer microarray demonstrates high specificity for thrombin, proving that a two-site binding assay with the TBA1 aptamer as capture layer...

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Detalles Bibliográficos
Autores principales: Meneghello, Anna, Sosic, Alice, Antognoli, Agnese, Cretaio, Erica, Gatto, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003437/
https://www.ncbi.nlm.nih.gov/pubmed/27605338
http://dx.doi.org/10.3390/microarrays1020095

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003437/
https://www.ncbi.nlm.nih.gov/pubmed/27605338
http://dx.doi.org/10.3390/microarrays1020095

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