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Hydrogel Microwell Arrays Allow the Assessment of Protease-Associated Enhancement of Cancer Cell Aggregation and Survival

Current routine cell culture techniques are only poorly suited to capture the physiological complexity of tumor microenvironments, wherein tumor cell function is affected by intricate three-dimensional (3D), integrin-dependent cell-cell and cell-extracellular matrix (ECM) interactions. 3D cell cultu...

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Detalles Bibliográficos
Autores principales: Loessner, Daniela, Kobel, Stefan, Clements, Judith A., Lutolf, Matthias P., Hutmacher, Dietmar W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003461/
https://www.ncbi.nlm.nih.gov/pubmed/27605189
http://dx.doi.org/10.3390/microarrays2030208