Influence of freeze-drying and γ-irradiation in preclinical studies of flurbiprofen polymeric nanoparticles for ocular delivery using d-(+)-trehalose and polyethylene glycol

This study investigated the suspension of poly(ε-caprolactone) nanoparticles as an ocular delivery system for flurbiprofen (FB-PεCL-NPs) in order to overcome the associated problems, such as stability, sterility, tolerance, and efficacy, with two different FB-PεCL-NP formulations. The formulations w...

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Detalles Bibliográficos
Autores principales: Ramos Yacasi, Gladys Rosario, García López, María Luisa, Espina García, Marta, Parra Coca, Alexander, Calpena Campmany, Ana Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003565/
https://www.ncbi.nlm.nih.gov/pubmed/27601897
http://dx.doi.org/10.2147/IJN.S105606

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003565/
https://www.ncbi.nlm.nih.gov/pubmed/27601897
http://dx.doi.org/10.2147/IJN.S105606

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