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Postsynaptic, not presynaptic NMDA receptors are required for spike timing dependent LTD induction

Long-term depression (LTD) between cortical layer 4 spiny stellate cells and layer 2/3 pyramidal cells requires the activation of NMDA receptors (NMDARs). In young rodents, this form of LTD has been repeatedly reported to require presynaptic NMDARs for its induction. Here we show that at this synaps...

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Detalles Bibliográficos
Autores principales: Carter, Brett C., Jahr, Craig E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003644/
https://www.ncbi.nlm.nih.gov/pubmed/27399842
http://dx.doi.org/10.1038/nn.4343