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When fast is better: protein folding fundamentals and mechanisms from ultrafast approaches

Protein folding research stalled for decades because conventional experiments indicated that proteins fold slowly and in single strokes, whereas theory predicted a complex interplay between dynamics and energetics resulting in myriad microscopic pathways. Ultrafast kinetic methods turned the field u...

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Detalles Bibliográficos
Autores principales: Muñoz, Victor, Cerminara, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003694/
https://www.ncbi.nlm.nih.gov/pubmed/27574021
http://dx.doi.org/10.1042/BCJ20160107