Systematic Discovery of Complex Indels in Human Cancers

Complex indels are formed by simultaneously deleting and inserting DNA fragments of different sizes at a common genomic location. Here, we present a systematic analysis of somatic complex indels in the coding sequences of over 8,000 cancer cases using Pindel-C. We discovered 285 complex indels in ca...

Descripción completa

Detalles Bibliográficos
Autores principales: Ye, Kai, Wang, Jiayin, Jayasinghe, Reyka, Lameijer, Eric-Wubbo, McMichael, Joshua F., Ning, Jie, McLellan, Michael D., Xie, Mingchao, Cao, Song, Yellapantula, Venkata, Huang, Kuan-lin, Scott, Adam, Foltz, Steven, Niu, Beifang, Johnson, Kimberly J., Moed, Matthijs, Slagboom, P. Eline, Chen, Feng, Wendl, Michael C., Ding, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003782/
https://www.ncbi.nlm.nih.gov/pubmed/26657142
http://dx.doi.org/10.1038/nm.4002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003782/
https://www.ncbi.nlm.nih.gov/pubmed/26657142
http://dx.doi.org/10.1038/nm.4002

Ejemplares similares