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An unusual UMP C-5 methylase in nucleoside antibiotic polyoxin biosynthesis

Polyoxin is a group of structurally-related peptidyl nucleoside antibiotics bearing C-5 modifications on the nucleoside skeleton. Although the structural diversity and bioactivity preference of polyoxin are, to some extent, affected by such modifications, the biosynthetic logic for their occurence r...

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Detalles Bibliográficos
Autores principales: Chen, Wenqing, Li, Yan, Li, Jie, Wu, Lian, Wang, Renxiao, Deng, Zixin, Zhou, Jiahai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003785/
https://www.ncbi.nlm.nih.gov/pubmed/27412636
http://dx.doi.org/10.1007/s13238-016-0289-y