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An unusual UMP C-5 methylase in nucleoside antibiotic polyoxin biosynthesis
Polyoxin is a group of structurally-related peptidyl nucleoside antibiotics bearing C-5 modifications on the nucleoside skeleton. Although the structural diversity and bioactivity preference of polyoxin are, to some extent, affected by such modifications, the biosynthetic logic for their occurence r...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Higher Education Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003785/ https://www.ncbi.nlm.nih.gov/pubmed/27412636 http://dx.doi.org/10.1007/s13238-016-0289-y |