Cellular model of neuronal atrophy induced by DYNC1I1 deficiency reveals protective roles of RAS-RAF-MEK signaling

Neuronal atrophy is a common pathological feature occurred in aging and neurodegenerative diseases. A variety of abnormalities including motor protein malfunction and mitochondrial dysfunction contribute to the loss of neuronal architecture; however, less is known about the intracellular signaling p...

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Detalles Bibliográficos
Autores principales: Liu, Zhi-Dong, Zhang, Su, Hao, Jian-Jin, Xie, Tao-Rong, Kang, Jian-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003791/
https://www.ncbi.nlm.nih.gov/pubmed/27510948
http://dx.doi.org/10.1007/s13238-016-0301-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003791/
https://www.ncbi.nlm.nih.gov/pubmed/27510948
http://dx.doi.org/10.1007/s13238-016-0301-6

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