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Cellular model of neuronal atrophy induced by DYNC1I1 deficiency reveals protective roles of RAS-RAF-MEK signaling
Neuronal atrophy is a common pathological feature occurred in aging and neurodegenerative diseases. A variety of abnormalities including motor protein malfunction and mitochondrial dysfunction contribute to the loss of neuronal architecture; however, less is known about the intracellular signaling p...
Autores principales: | Liu, Zhi-Dong, Zhang, Su, Hao, Jian-Jin, Xie, Tao-Rong, Kang, Jian-Sheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Higher Education Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003791/ https://www.ncbi.nlm.nih.gov/pubmed/27510948 http://dx.doi.org/10.1007/s13238-016-0301-6 |
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