NOTCH1 Inhibits Activation of ATM by Impairing the Formation of an ATM-FOXO3a-KAT5/Tip60 Complex

The DNA damage response (DDR) signal transduction pathway is responsible for sensing DNA damage and further relaying this signal into the cell. ATM is an apical DDR kinase that orchestrates the activation and the recruitment of downstream DDR factors to induce cell-cycle arrest and repair. We have p...

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Detalles Bibliográficos
Autores principales: Adamowicz, Marek, Vermezovic, Jelena, d’Adda di Fagagna, Fabrizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003812/
https://www.ncbi.nlm.nih.gov/pubmed/27524627
http://dx.doi.org/10.1016/j.celrep.2016.07.038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003812/
https://www.ncbi.nlm.nih.gov/pubmed/27524627
http://dx.doi.org/10.1016/j.celrep.2016.07.038

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