Molecular Principles of Gene Fusion Mediated Rewiring of Protein Interaction Networks in Cancer

Gene fusions are common cancer-causing mutations, but the molecular principles by which fusion protein products affect interaction networks and cause disease are not well understood. Here, we perform an integrative analysis of the structural, interactomic, and regulatory properties of thousands of p...

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Detalles Bibliográficos
Autores principales: Latysheva, Natasha S., Oates, Matt E., Maddox, Louis, Flock, Tilman, Gough, Julian, Buljan, Marija, Weatheritt, Robert J., Babu, M. Madan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003813/
https://www.ncbi.nlm.nih.gov/pubmed/27540857
http://dx.doi.org/10.1016/j.molcel.2016.07.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003813/
https://www.ncbi.nlm.nih.gov/pubmed/27540857
http://dx.doi.org/10.1016/j.molcel.2016.07.008

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