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Molecular Principles of Gene Fusion Mediated Rewiring of Protein Interaction Networks in Cancer
Gene fusions are common cancer-causing mutations, but the molecular principles by which fusion protein products affect interaction networks and cause disease are not well understood. Here, we perform an integrative analysis of the structural, interactomic, and regulatory properties of thousands of p...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003813/ https://www.ncbi.nlm.nih.gov/pubmed/27540857 http://dx.doi.org/10.1016/j.molcel.2016.07.008 |