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Deep Proteome Analysis Identifies Age-Related Processes in C. elegans

Effective network analysis of protein data requires high-quality proteomic datasets. Here, we report a near doubling in coverage of the C. elegans adult proteome, identifying >11,000 proteins in total with ∼9,400 proteins reproducibly detected in three biological replicates. Using quantitative ma...

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Detalles Bibliográficos
Autores principales: Narayan, Vikram, Ly, Tony, Pourkarimi, Ehsan, Murillo, Alejandro Brenes, Gartner, Anton, Lamond, Angus I., Kenyon, Cynthia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003814/
https://www.ncbi.nlm.nih.gov/pubmed/27453442
http://dx.doi.org/10.1016/j.cels.2016.06.011