Comprehensive Identification of RNA-Binding Domains in Human Cells

Mammalian cells harbor more than a thousand RNA-binding proteins (RBPs), with half of these employing unknown modes of RNA binding. We developed RBDmap to determine the RNA-binding sites of native RBPs on a proteome-wide scale. We identified 1,174 binding sites within 529 HeLa cell RBPs, discovering...

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Detalles Bibliográficos
Autores principales: Castello, Alfredo, Fischer, Bernd, Frese, Christian K., Horos, Rastislav, Alleaume, Anne-Marie, Foehr, Sophia, Curk, Tomaz, Krijgsveld, Jeroen, Hentze, Matthias W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003815/
https://www.ncbi.nlm.nih.gov/pubmed/27453046
http://dx.doi.org/10.1016/j.molcel.2016.06.029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003815/
https://www.ncbi.nlm.nih.gov/pubmed/27453046
http://dx.doi.org/10.1016/j.molcel.2016.06.029

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