Cargando…

Alterations of Phosphodiesterases in Adrenocortical Tumors

Alterations in the cyclic (c)AMP-dependent signaling pathway have been implicated in the majority of benign adrenocortical tumors (ACTs) causing Cushing syndrome (CS). Phosphodiesterases (PDEs) are enzymes that regulate cyclic nucleotide levels, including cyclic adenosine monophosphate (cAMP). Inact...

Descripción completa

Detalles Bibliográficos
Autores principales: Hannah-Shmouni, Fady, Faucz, Fabio R., Stratakis, Constantine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003917/
https://www.ncbi.nlm.nih.gov/pubmed/27625633
http://dx.doi.org/10.3389/fendo.2016.00111