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Implication of Genetic Deletion of Wdr13 in Mice: Mild Anxiety, Better Performance in Spatial Memory Task, with Upregulation of Multiple Synaptic Proteins

WDR13 expresses from the X chromosome and has a highly conserved coding sequence. There have been multiple associations of WDR13 with memory. However, its detailed function in context of brain and behavior remains unknown. We characterized the behavioral phenotype of 2 month old male mice lacking th...

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Detalles Bibliográficos
Autores principales: Mitra, Shiladitya, Sameer Kumar, Ghantasala S., Tiwari, Vivek, Lakshmi, B. Jyothi, Thakur, Suman S., Kumar, Satish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003927/
https://www.ncbi.nlm.nih.gov/pubmed/27625594
http://dx.doi.org/10.3389/fnmol.2016.00073