Knockout of Myostatin by Zinc-finger Nuclease in Sheep Fibroblasts and Embryos

Myostatin (MSTN) can negatively regulate the growth and development of skeletal muscle, and natural mutations can cause “double-muscling” trait in animals. In order to block the inhibiting effect of MSTN on muscle growth, we transferred zinc-finger nucleases (ZFN) which targeted sheep MSTN gene into...

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Detalles Bibliográficos
Autores principales: Zhang, Xuemei, Wang, Liqin, Wu, Yangsheng, Li, Wenrong, An, Jing, Zhang, Fuchun, Liu, Mingjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Asian-Australasian Association of Animal Production Societies (AAAP) and Korean Society of Animal Science and Technology (KSAST) 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003977/
https://www.ncbi.nlm.nih.gov/pubmed/27189642
http://dx.doi.org/10.5713/ajas.16.0130

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003977/
https://www.ncbi.nlm.nih.gov/pubmed/27189642
http://dx.doi.org/10.5713/ajas.16.0130

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