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Microbial and Natural Metabolites That Inhibit Splicing: A Powerful Alternative for Cancer Treatment

In eukaryotes, genes are frequently interrupted with noncoding sequences named introns. Alternative splicing is a nuclear mechanism by which these introns are removed and flanking coding regions named exons are joined together to generate a message that will be translated in the cytoplasm. This mech...

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Detalles Bibliográficos
Autores principales: Martínez-Montiel, Nancy, Rosas-Murrieta, Nora Hilda, Martínez-Montiel, Mónica, Gaspariano-Cholula, Mayra Patricia, Martínez-Contreras, Rebeca D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004037/
https://www.ncbi.nlm.nih.gov/pubmed/27610372
http://dx.doi.org/10.1155/2016/3681094