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Microbial and Natural Metabolites That Inhibit Splicing: A Powerful Alternative for Cancer Treatment
In eukaryotes, genes are frequently interrupted with noncoding sequences named introns. Alternative splicing is a nuclear mechanism by which these introns are removed and flanking coding regions named exons are joined together to generate a message that will be translated in the cytoplasm. This mech...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Hindawi Publishing Corporation
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004037/ https://www.ncbi.nlm.nih.gov/pubmed/27610372 http://dx.doi.org/10.1155/2016/3681094 |