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Nucleus Accumbens Shell and mPFC but Not Insula Orexin-1 Receptors Promote Excessive Alcohol Drinking

Addiction to alcohol remains a major social and economic problem, in part because of the high motivation for alcohol that humans exhibit and the hazardous binge intake this promotes. Orexin-1-type receptors (OX1Rs) promote reward intake under conditions of strong drives for reward, including excessi...

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Detalles Bibliográficos
Autores principales: Lei, Kelly, Wegner, Scott A., Yu, Ji Hwan, Mototake, Arisa, Hu, Bing, Hopf, Frederic W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004043/
https://www.ncbi.nlm.nih.gov/pubmed/27625592
http://dx.doi.org/10.3389/fnins.2016.00400