SOX9-regulated cell plasticity in colorectal metastasis is attenuated by rapamycin

The cancer stem cell (CSC) hypothesis proposes a hierarchical organization of tumors, in which stem-like cells sustain tumors and drive metastasis. The molecular mechanisms underlying the acquisition of CSCs and metastatic traits are not well understood. SOX9 is a transcription factor linked to stem...

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Detalles Bibliográficos
Autores principales: Carrasco-Garcia, Estefania, Lopez, Lidia, Aldaz, Paula, Arevalo, Sara, Aldaregia, Juncal, Egaña, Larraitz, Bujanda, Luis, Cheung, Martin, Sampron, Nicolas, Garcia, Idoia, Matheu, Ander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004104/
https://www.ncbi.nlm.nih.gov/pubmed/27571710
http://dx.doi.org/10.1038/srep32350

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004104/
https://www.ncbi.nlm.nih.gov/pubmed/27571710
http://dx.doi.org/10.1038/srep32350

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