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Forced co-expression of IL-21 and IL-7 in whole-cell cancer vaccines promotes antitumor immunity
Genetic modification of whole-cell cancer vaccines to augment their efficacies has a history of over two and a half decades. Various genes and gene combinations, targeting different aspects of immune responses have been tested in pursuit of potent adjuvant effects. Here we show that co-expression of...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004106/ https://www.ncbi.nlm.nih.gov/pubmed/27571893 http://dx.doi.org/10.1038/srep32351 |