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Mammalian non-CG methylations are conserved and cell-type specific and may have been involved in the evolution of transposon elements

Although non-CG methylations are abundant in several mammalian cell types, their biological significance is sparsely characterized. We gathered 51 human and mouse DNA methylomes from brain neurons, embryonic stem cells and induced pluripotent stem cells, primordial germ cells and oocytes. We utilize...

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Detalles Bibliográficos
Autores principales: Guo, Weilong, Zhang, Michael Q., Wu, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004121/
https://www.ncbi.nlm.nih.gov/pubmed/27573482
http://dx.doi.org/10.1038/srep32207