High Mobility Group Box Protein 1 Boosts Endothelial Albumin Transcytosis through the RAGE/Src/Caveolin-1 Pathway

High-mobility group box protein 1 (HMGB1), an inflammatory mediator, has been reported to destroy cell-cell junctions, resulting in vascular endothelial hyperpermeability. Here, we report that HMGB1 increases the endothelial transcytosis of albumin. In mouse lung vascular endothelial cells (MLVECs),...

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Detalles Bibliográficos
Autores principales: Shang, Dan, Peng, Tao, Gou, Shanmiao, Li, Yiqing, Wu, Heshui, Wang, Chunyou, Yang, Zhiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004123/
https://www.ncbi.nlm.nih.gov/pubmed/27572515
http://dx.doi.org/10.1038/srep32180

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004123/
https://www.ncbi.nlm.nih.gov/pubmed/27572515
http://dx.doi.org/10.1038/srep32180

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